FAQ about Hepatitis B

1. If I have chronic HBV can I breast feed my babytrue. At 0, 1 and 6 months they have been
without worrying that he might get infected?administered the first two doses of 10 micrograms
A study made in Texas on 101 breast-fed infants andwith Merck Sharpe and Dohme's recombinant DNA
268 formula-fed infants after immunopropylaxis was(MSD rDNA) vaccine (Recombivax HB). At month 6,
applied showed that there is no risk in breast feedingthe tested subjects received SmithKline Beecham's
your baby if you have chronic HBV. Appropriaterecombinant DNA (SB rDNA) vaccine (Engerix-B). At
immunoprophilaxies means administering hepatitis Bthe end of the vaccination program, the results were
immune globulin and hepatitis B vaccine.the same with the usuall cases when people get one
2. Does breast feeding have any consequence upontype of recombinant DNA vaccine, so there is no
immunoprophylaxis, like leading to its failure?harm in completing one type of vaccine with another.
It has been observed that the risk of5. Is hepatitis B vaccine safe if administered during
immunoprofilaxis failure is approximately equal inpregnancy?
breast fed babies of chronic HBV mothers and bottleScientists say that the vaccination does not lead to
fed babies. Also, breast feeding does not influenceany congenital malformation or miscarriage, it is high
the response of anti-HBs in any negative ways.immunogenic and protects babies in the immediate
3. Can a baby get HBV from its mother even duringneonatal period. Doctors are still hesitant in
pregnancy, and what can be done about that?administering all kind of vaccine during pregnancy, but
Yes, the virus can transmit to the baby even duringthe hepatitis B vaccine seems to be one of the few
pregnancy, in fact this being one of the mostthat can be given to a pregnant woman without
frequent ways of increasing the number of carriers incausing damage.
the world. If a mother has HBV she can get6. Can still I use a vial of Hepatitis B vaccine if I kept
intramuscular shots of HBV specific immunoglobulinit out of the refrigerator for a few days?
(HBIG) during pregnancy and so this stops the virusTests have shown that after keeping the vial at 37
from infecting the foetus. This solution is not 100%degrees C for 1 week the immunogenicity and
effective and 10%-20% of the babies still get HBV inreactogenicity of the vaccine were not altered and
their early life.the vaccine's properties were intact. This is a good
4. Can hepatitis B vaccination schedule initiated withthing, especially for those who live in a country
one recombinant DNA vaccine be completed withwhere facilities for proper storage and transportation
another?are not adequate yet.
Studies have been made on 48 adults to see if this is