What are Antibodies

Antibodies, also called immunoglobulins are largeneutralize the foreign body. The production of
y-shaped proteins which function to identify and helpantibodies by B-cells is the main function of the
remove foreign antigens such as viruses and bacteria.humoral immune system.
In mammals there are five main types of antibodiesAutoimmune disorders can usually be traced to
including: IgA, IgD, IgE, IgG, and IgM. There are 4 IgGantibodies which bind the body's own proteins or
and 2 IgA subtypes present in humans.epitopes, and these types of antibodies can be
Antibodies are created by plasma cells which aredetected through serological blood tests. Due to the
derived from the B-cells in the immune system. Dueamazing specificity of antibodies, they have some
to the fact that antibodies exist freely in theimportant practical applications in both medicine for
bloodstream or bound to cell membranes, they arethe detection of HIV and other viruses in blood, and
said to be part of the humoral immune system.in research to purify and detect proteins in the study
Every different antibody recognizes a specific foreignof molecular biology. For example, currently medicine
antigen. This is because the two tips of its "Y" areis using biotechnologically designed monoclonal
different to each antibody are allow differentantibodies which work as an antibody therapy. These
antibodies to bind to different foreign antigens. Whenmethods are being employed recently and are the
the antibody binds to a bacteria, it tags the microberesult of numerous clinical trials in a number of
or virus for attack by the immune system such asdiseases including cancer, and rheumatoid arthritis.
killer T-cells. Sometimes, antibodies can directly